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ea0015p137 | Diabetes, metabolism and cardiovascular | SFEBES2008

Effects of Persea americana Mill (Lauraceae) (‘Avocado’) ethanolic leaf extract (PAE) on blood glucose and kidney function in streptozotocin (STZ)-induced diabetic rats and on kidney cell lines of the proximal (LLC-PK1) and distal tubules (MDBK)

Musabayane Cephas T , Gondwe Mavuto , Kamadyaapa Dave , Tufts Mark A , Chuturgoon Anil A

We investigated effects of ethanolic Persea americana Mill. (Avocado) leaf extracts (PAE) on blood glucose and kidney function in rats. Extracts of the plant have been employed to treat hypertension and diabetes mellitus. Oral glucose tolerance tests (OGTT) were conducted in fasted non-diabetic and STZ-diabetic rats following a glucose load (0.86 g/kg, p.o.), followed by various PAE doses (60, 120 and 240 mg/kg). Rats treated with deionised water or standard...

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Endocrine Abstracts

Effects of Persea americana Mill (Lauraceae) (‘Avocado’) ethanolic leaf extract (PAE) on blood glucose and kidney function in streptozotocin (STZ)-induced diabetic rats and on kidney cell lines of the proximal (LLC-PK1) and distal tubules (MDBK)

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